Ground Beef Casserole loaded with beef, cheese, and egg noodles is sure to be a family favorite.

Ground Beef Casserole

 

I can never get enough of cooking or eating casseroles. They’re easy to make, filling, and just have a way of comforting the soul.

Sour cream, cream cheese, cheddar cheese, Parmesan cheese, and mozzarella cheese (yes there’s really that much cheese) make this casserole sinfully rich and gooey. Served with a side salad and some crusty bread, this will easily last 2 meals for a family of four.

It can also be assembled, frozen and defrosted overnight in the refrigerator. Then bake according to recipe directions.

Ground Beef Casserole

I don’t know what it is about egg noodles, but I absolutely love them. Their flavor and shape is a nice change up from pasta. I’m still Jenny Craiging it this week (down 3 pounds and halfway to my goal in 1 week!) so no foods like Ground Beef Casserole for me this week.

However I could use the comfort of a delicious casserole today because in exactly 1 week my son will be having major surgery in Indianapolis to remove his retroperitoneal lymph nodes. He recently completed chemotherapy for testicular cancer and his tumor markers have come down to the normal range, but he needs to have some lymph nodes removed. Something called RPLND surgery. A doctor named Richard Foster at Indiana University is widely considered the best surgeon in the world for doing this type of surgery and he will be my son’s surgeon.

If anyone lives in the Indianapolis area we would love to hear some restaurant suggestions especially places that are good for take out and are near the IU Medical Complex since we will be there 8 days. We’ve been to Bru Burger and boy do they ever have fantastic burgers ๐Ÿ™‚

Ground Beef Casserole

Love that cheese ๐Ÿ™‚ ๐Ÿ™‚

Ground Beef Casserole

Watch the short video below to see how easy this recipe is!

Ground Beef Casserole

4.81 from 103 votes

By Christin Mahrlig

Prep: 15 minutes
Cook: 40 minutes
Total: 55 minutes
Servings: 6
A hearty Italian-style casserole of ground beef, egg noodles, and gobs of cheese.
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Ingredients

  • 1 pound ground round
  • 1 (14 1/2-ounce) can diced tomatoes with basil,, garlic, and oregano, undrained
  • 1 (10-ounce) can Rotel tomatoes
  • 1 (6-ounce) can tomato paste
  • 1 teaspoon salt
  • 1 teaspoon sugar
  • 3/4 teaspoon Italian seasoning
  • 1/4 teaspoon pepper
  • 3 cups uncooked medium egg noodles
  • 5 green onions,, chopped
  • 1 (8-ounce) container sour cream
  • 1 (3-ounce) package cream cheese,, softened
  • 1 cup shredded Cheddar cheese
  • 1 cup shredded Parmesan cheese
  • 1 cup shredded mozzarella cheese

Instructions 

  • Place a large skillet over medium heat and add ground round. Cook, breaking up with a wooden spoon, until no longer pink.
  • Add both cans of tomatoes, tomato paste, salt, sugar, Italian seasoning, and pepper. Stir to mix and let simmer over low heat while you get the rest of the ingredients ready.
  • Preheat oven to 350 degrees. Cook egg noodles according to package directions and drain well.
  • In a medium bowl, stir together noodles, green onions, sour cream, and cream cheese.
  • Spoon noodle mixture into a greased 13X9-inch baking dish. Top with beef mixture. Sprinkle with cheeses.
  • Spray a piece of aluminum foil with cooking spray and place cooking spray side down on top of baking dish to cover.
  • Bake for 35 minutes. Uncover and bake 5 more minutes.

Nutrition

Calories: 501kcal

Nutrition information is automatically calculated, so should only be used as an approximation.

Did you make this?Leave a comment below and tag us @spicysouthernkitchen on social media!

Recipe Source: adapted from Southern Living

Homestyle Ground Beef Casserole

Disclosure: This post contains affiliate links.

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272 Comments

  1. Kristi @ Inspiration Kitchen says:

    Ooey, gooey goodness in a casserole! I love these type of meals. So comforting! Sending good thoughts your way for your son’s surgery!

  2. Shirley C says:

    Just wanted you to know that I made this casserole tonight and my husband and I thought is was delicious!

  3. Beth @ bethcakes says:

    This looks like the best and cheesiest casserole I’ve ever seen! Hope everything goes well with your son’s surgery!

  4. Aimee / WallflowerGirl.co.uk says:

    This looks insanely good… all that cheese is making me drool!

  5. marcie says:

    I’m with you on casseroles, Christin — they’re the best — especially when filled meat and cheese! I wish your son the best for his surgery and I will keep you and your family in my thoughts and prayers!!

    1. Christin Mahrlig says:

      It’s hard to go wrong with meat and cheese ๐Ÿ™‚
      Thank you so much for your prayers Marcie!

  6. Bam's Kitchen says:

    My thoughts and prayers go out to your son. (I know it is worrying and that is exactly what us moms do– we worry. ) wishing him a quick recovery.

    This pasta bake is going to be a big hit with my always hungry teenage boys. Love the recipe. Take Care, BAM

    1. Christin Mahrlig says:

      Thank You! Sometimes I don’t think I’ve stopped worrying since I became a mom.

  7. Medeja says:

    Oh that cheese looks really good ๐Ÿ™‚ what a filling warming dish ๐Ÿ™‚

    1. Christin Mahrlig says:

      Thanks Medejo ๐Ÿ™‚

  8. Nicole ~ Cooking for Keeps says:

    The cheese!!!!!!! This looks so comforting and delicious. Thinking about you and your family!!

  9. ATasteOfMadness says:

    All that cheese is making me swoon!! I want some of this for dinner ๐Ÿ™‚

  10. Amy (Savory Moments) says:

    This looks super delicious – I’ve never had this type of casserole before. Best wishes to your son on his upcoming surgery and to you as well!! Take care.