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Homestyle Ground Beef Casserole

Ground Beef Casserole loaded with beef, cheese, and egg noodles is sure to be a family favorite.

Ground Beef Casserole

 

I can never get enough of cooking or eating casseroles. They’re easy to make, filling, and just have a way of comforting the soul.

Sour cream, cream cheese, cheddar cheese, Parmesan cheese, and mozzarella cheese (yes there’s really that much cheese) make this casserole sinfully rich and gooey. Served with a side salad and some crusty bread, this will easily last 2 meals for a family of four.

It can also be assembled, frozen and defrosted overnight in the refrigerator. Then bake according to recipe directions.

Ground Beef Casserole

I don’t know what it is about egg noodles, but I absolutely love them. Their flavor and shape is a nice change up from pasta. I’m still Jenny Craiging it this week (down 3 pounds and halfway to my goal in 1 week!) so no foods like Ground Beef Casserole for me this week.

However I could use the comfort of a delicious casserole today because in exactly 1 week my son will be having major surgery in Indianapolis to remove his retroperitoneal lymph nodes. He recently completed chemotherapy for testicular cancer and his tumor markers have come down to the normal range, but he needs to have some lymph nodes removed. Something called RPLND surgery. A doctor named Richard Foster at Indiana University is widely considered the best surgeon in the world for doing this type of surgery and he will be my son’s surgeon.

If anyone lives in the Indianapolis area we would love to hear some restaurant suggestions especially places that are good for take out and are near the IU Medical Complex since we will be there 8 days. We’ve been to Bru Burger and boy do they ever have fantastic burgers 🙂

Ground Beef Casserole

Love that cheese 🙂 🙂

Ground Beef Casserole

Watch the short video below to see how easy this recipe is!

Ground Beef Casserole

Ground Beef Casserole

A hearty Italian-style casserole of ground beef, egg noodles, and gobs of cheese.
PREP: 15 minutes
COOK: 40 minutes
TOTAL: 55 minutes
SERVINGS: 6

Ingredients

  • 1 pound ground round
  • 1 (14 1/2-ounce) can diced tomatoes with basil, garlic, and oregano, undrained
  • 1 (10-ounce) can Rotel tomatoes
  • 1 (6-ounce) can tomato paste
  • 1 teaspoon salt
  • 1 teaspoon sugar
  • 3/4 teaspoon Italian seasoning
  • 1/4 teaspoon pepper
  • 3 cups uncooked medium egg noodles
  • 5 green onions, chopped
  • 1 (8-ounce) container sour cream
  • 1 (3-ounce) package cream cheese, softened
  • 1 cup shredded Cheddar cheese
  • 1 cup shredded Parmesan cheese
  • 1 cup shredded mozzarella cheese

Instructions

  • Place a large skillet over medium heat and add ground round. Cook, breaking up with a wooden spoon, until no longer pink.
  • Add both cans of tomatoes, tomato paste, salt, sugar, Italian seasoning, and pepper. Stir to mix and let simmer over low heat while you get the rest of the ingredients ready.
  • Preheat oven to 350 degrees. Cook egg noodles according to package directions and drain well.
  • In a medium bowl, stir together noodles, green onions, sour cream, and cream cheese.
  • Spoon noodle mixture into a greased 13X9-inch baking dish. Top with beef mixture. Sprinkle with cheeses.
  • Spray a piece of aluminum foil with cooking spray and place cooking spray side down on top of baking dish to cover.
  • Bake for 35 minutes. Uncover and bake 5 more minutes.

Nutrition

Calories: 501kcal
Author: Christin Mahrlig
Course: Casserole
Cuisine: American

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Recipe Source: adapted from Southern Living

Homestyle Ground Beef Casserole

Disclosure: This post contains affiliate links.

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268 thoughts on “Homestyle Ground Beef Casserole”

  1. This recipe is nothing more than good old fashioned goulash.
    You cannot ruin it. Tomatoes or sauce or Prego. Any noodle,
    no yolk, chinese, pasta, gluten free. Whatever. Make it to suit your
    households palates and allergies!

    1. Misty motter

      It does not say anything about draining the hamburger after u cook it I know that’s a stupid question but I was confused on that

      1. Jonathan Russo

        I drain it now after finding it too water the first time I made. I also drain the diced tomatoes

  2. How much cauliflower would you use to substitute for the pasta? Would you use cauliflower florets or rice? If So, how much and would you cook before? Thanks. This looks delicious!

    1. I would definitely cook the cauli half-way before assembling the casserole. I hope it turns out good!

  3. this recipe looks so so good I want to try it but just wanted to know if maybe we can use chicken instead?? trying it with beef but just wanted to know if anyones tried it with chicken?

    1. I made this tonight. Very good. But you know I bet made with chicken with a white cheesy sauce would be so good. Gonna try it tomorrow. Yum

    2. Ground turkey works well. I season while browning with Trappey’s Bull Sauce. People believe it’s beef all the time.

      1. Where did you buy that seasoning? I just made this for dinner and it’s in the oven now, hope it tastes ok

  4. My children are deathly allergic to eggs – so no egg noodles. But they really would like this dish – any thoughts on another noodle type that would work well in this casserole? Or another substitute? (but my boys unfortunately aren’t going to eat cauliflower etc).

    Thank you

    1. You can buy no yolk noodles in bigger grocery stores. Have used them many times – they taste like noodles. It is usually the yolk to which people are allergic. Check with your doctor to make sure.

    2. I used spaghetti squash……we haven’t used pasta in over a year now…….spaghetti squash is the bomb

  5. Making this tonight for dinner, with just a few tweaks since I am lactose intolerant. But I will find a way and I’m sure it will be amazing!

  6. For people that can’t eat that much cheese this is really ruined, so I am very disappointed. Cream cheese and sour cream oh lord help me!! I would be so sick! I guess people think everyone can can eat that or likes it… a very little cheese on top goes a long ways.

    1. This is simply a recipe that you need to skip, not complain for it to be altered to accommodate you, when everyone else seems to enjoy it and can have cheese

    2. I agree. Skip it if it’s something you can’t have. I exchange fat free plain Greek yogurt in place of sour cream. I think I’m going to try this recipe!

    3. Soy cream cheese and soy sour cream would work well for you and I for one can’t taste the difference. There are also cheese substitutes—some better than others. Look for one made with cashews. BTW, cashew cream is VERY good and can be used as a substitute for cream.

    4. Well Lori, don’t eat it? I don’t like peanuts, but I don’t comment of recipes that have peanuts and say that it’s ruined or that people think everyone likes peanuts. I just don’t comment, I move on, I find a recipe that sounds good. One that works for me. I don’t need to let everyone know how disappointed I am about said recipe.

      I’m disappointed in you Lori. I guess you think we shouldn’t enjoy cheese because you can’t?

      **Carry on

    5. Terry Pleasants

      Sounds like this isn’t the recipe for you Lori! Mine’s in the oven now. Can’t wait to serve it tomorrow with my Christmas dinner. I think my family will enjoy it.

    6. There is tons of recipes that I cant eat because of peanut allergies… I dont bitch about it and go on about how it should be altered. Many people love these ingredients as the same with alot of peanut butter recipes. Move on and look for more accommodating recipes if this one isnt for you.

    7. Michelle A Boyce

      My goodness.No need to be snarky and rude just because someone has a personal negative opinion.
      How about you don’t read it and pass on by unless you have useful suggestions.

      1. Wow…bet her mom had a fun time raising her. This recipe is just fine…look for another one that fits diet. Pinterest does have a nice search function …you know?

    1. I am making this tonight, with the side being sautéed zucchini, onions, red bell peppers and whatever else I decide to add. Add a little (or a lot) of garlic.

  7. We eat a Ketogenic Diet/Lifestyle, little/no carbs. Substituted cauliflower for the noodles. HUGE hit!

    1. I was thinking of doing this keto-style as well with spiralized butternut squash noodles. Worth a try!

      1. Christine Wilkinson

        I’m keto as well … was thinking of Konjak noodles. Use them all the time for speggetti. No carbs!

    2. I see the caolories count but I count protein and carb calories! What are those????. I times my protein gram X 4 and also my carbd and fats! Need those numbrs!!!,

  8. Sounds yummy, I’m heading to the store to get things I don’t have to make for dinner tonight!
    I’m originally from Indiana, my daughter had an autoimmune disorder we had treated at Riley
    Great choices for treating children in Indy
    I hope you and your family are doing well

  9. My kids won’t eat the tomatoes, is there something else I could substitute for those two ingredients?

  10. This looks delicious—I am a big fan of cheese and ground beef–well everything in this recipe except the green onions, which I will leave out.
    I have one question, I noticed in the video, you poured the gb mixture over the noodles–does the ground beef mixture cook down between the noodles?

  11. I am making this tonight for my three boys. I hope that your son is okay – I am truly so sorry that you are going through this. I can’t imagine how difficult it has been for you. My thoughts are with you and your family.

  12. Dante Owens

    Just made tonight and I did just a bit different recipe. I used tomato sauce and added heavy cream so it wouldn’t be dry. I added ground sausage as well. I know I got off the path, but I’m a southerner. Lol Other than that great recipe!!!

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