In a large nonstick pan, cook and crumble ground beef. When it is no longer pink, add onion and jalapeno and cook until soft.
Add can of green chilies, taco seasoning, and 1/4 cup water. Cook 1 minute. Remove from heat and set aside.
In a medium bowl, stir together sour cream, mayonnaise, and cheddar cheese. Set aside.
In another medium bowl, combine biscuit mix and 1/3 cup water and stir until a soft dough forms.
Coat an 8x8-inch pan with cooking spray. Add dough to pan and pat down and spread so that it covers the bottom and extends some up the sides.
Layer beef, then tomatoes, and sour cream mixture over the dough. Sprinkle with paprika.
Place in 375 degree oven for 25 to 30 minutes. Cut into squares and serve with avocado and shredded lettuce, if desired.