Preheat oven to 350 degrees F. and line a rimmed baking sheet with foil.
In a large bowl, stir together all meatloaf ingredients until evenly mixed.
Shape mixture into a 11x5-inch meatloaf on the prepared baking sheet.
Top with bacon slices, placing each slice so that one end is at the middle of the top of the meatloaf and the other end is at the bottom side and they are at a slight angle. Alternate them to the 2 sides.
In a small bowl stir together ketchup, brown sugar, dry mustard, Worcestershire sauce, and cayenne pepper. Brush half the ketchup mixture on the top and sides of the meatloaf.
Bake for 45 minutes. Brush remianing ketchup mixture on and bake another 30 minutes. Let cool 10 minutes before slicing.