Place peanuts in a greased 4 -quart slow cooker.
Combine both sugars, water, butter, TABASCO Sauce, Worcestershire sauce, chili powder, and cayenne pepper in a small bowl. Pour over peanuts.
Cover and cook on HIGH for 1 1/2 hours, stirring once or twice during cooking time..
Spread out on parchment paper to cool.
Store in an airtight container.